There is no research on the effects of adrenal gland tumors on polygraph accuracy. Note that polygraphy has not been demonstrated through peer-reviewed research to reliably detect deception in individuals who have no serious medical condition, let alone those who do, and the best peer-reviewed field studies suggest that "if a subject fails a polygraph, the probability that she is, in fact, being deceptive is little more than chance alone; that is, one could flip a coin and get virtually the same result for a positive test based on the published data."